Bio: 2008-07-06

Hepatitis Delta Virus (Current Topics in Microbiology and Immunology)

Hepatitis delta virus which causes severe acute and chronic liver disease was discovered following the detection of a novel antigen-antibody system in hepatitis B virus carriers. Currently, HDV is classified as a subviral satellite of hepatitis B virus. However, unlike other satellite viruses, the dependence of HDV on HBV is limited solely to the provision of an envelope of hepatitis B surface antigen for virus assembly. Research into the molecular virology of the HDV life cycle has revealed a fascinating collection of biology. These insights are now beginning to be translated into new potential treatment strategies. There are currently still an estimated 15 million HDV carriers worldwide.
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Insects as Natural Enemies: A Practical Perspective

Insects as Natural Enemies: A Practical Perspective
Publisher:Springer | 2005-08-05 | ISBN 1402017340 | Pages: 748 | PDF | 17 Mb

Over the past three decades there has been a dramatic increase in theoretical and practical studies on insect natural enemies. The appeal of insect predators, and parasitoids in particular, as research animals derives from the relative ease with which many species may be cultured and experimented with in the laboratory, the simple life cycles of most parasitoids, and the increasing demand for biological pest control.

There is now a massive literature on insect natural enemies, so there is a great need for a general text that the enquiring student or research worker can use in deciding on approaches and techniques that are appropriate to the study and evaluation of such insects. This book fulfils that demand. A considerably updated and expanded version of a previous best-seller, it is an account of major aspects of the biology of predators and parasitoids, punctuated with information and advice on which experiments or observations to conduct, and how to carry them out. Guidance is provided, where necessary, on the literature that may need to be consulted on particular topics.

While researchers can now refer to several books on parasitoids and predators, Insects as Natural Enemies is unique in emphasising practicalities. It is aimed at students and professional working in universities and both government and commercial institutes in the fields of pest management, agriculture, horticulture and forestry.
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Brian Morris , "Insects and Human Life"

Brian Morris , "Insects and Human Life"
Berg Publishers (September 29, 2005) | ISBN: 1845200756 | 320 pages | PDF | 1,8 Mb

What is the cultural importance of insects? Why do we spend a good deal of time and money in the West trying to exterminate insects? How are human-insect relations far more subtle in other societies? From bathtub-invaders to protein-source, insects play a multi-faceted role that has not previously been recognized. To investigate this fully, Brian Morris spent years in Malawi. Here, as in many tropical regions, insects have a profound impact on agriculture, the household, disease, and hence on oral literature, music, art, folklore, recreation, and religion. Much of the complexity of human-insect relations rests on paradox: insects may represent the source of contagion, but are also integral to many folk remedies. Weaving science with personal observations, Morris demonstrates an intimate knowledge of virtually every aspect of human-insect relations. It is the first study of this uncharted territory--the insect world that surrounds us and how we relate to it.
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Genome: The Autobiography of a Species in 23 Chapters (P.S.)

Genome: The Autobiography of a Species in 23 Chapters (P.S.)
Harper Perennial | 0060894083 | Edition -2006-06-01 | PDF | 368 pages | 1.57 MB | Rapidshare & Megaupload

The genome's been mapped.But what does it mean? Arguably the most significant scientific discovery of the new century, the mapping of the twenty-three pairs of chromosomes that make up the human genome raises almost as many questions as it answers. Questions that will profoundly impact the way we think about disease, about longevity, and about free will. Questions that will affect the rest of your life.
Genome offers extraordinary insight into the ramifications of this incredible breakthrough. By picking one newly discovered gene from each pair of chromosomes and telling its story, Matt Ridley recounts the history of our species and its ancestors from the dawn of life to the brink of future medicine. From Huntington's disease to cancer, from the applications of gene therapy to the horrors of eugenics, Matt Ridley probes the scientific, philosophical, and moral issues arising as a result of the mapping of the genome. It will help you understand what this scientific milestone means for you, for your children, and for humankind.

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The Microbial Models of Molecular Biology: From Genes to Genomes

The Microbial Models of Molecular Biology: From Genes to Genomes
Oxford University Press| 0195154363 | Edition - 2003 | PDF | 337pages| 1.94 MB | Rapidshare & Megaupload

This book explains the role of simple biological model systems in the growth of molecular biology. Essentially the whole history of molecular biology is presented here, tracing the work in bacteriophages in E. coli, the role of other prokaryotic systems, and also the protozoan and algal models - Paramecium and Chlamydomonas, primarily - and the move into eukaryotes with the fungal systems - Neurospora, Aspergillus and yeast. Each model was selected for its appropriateness for asking a given class of questions, and each spawned its own community of investigators. Some individuals made the transition to a new model over time, and remnant communities of investigators continue to pursue questions in all these models, as the cutting edge of molecular biological research flowed onward from model to model, and onward into higher organisms and, ultimately, mouse and man.

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Denis Noble, The Music of Life: Biology beyond the Genome

Denis Noble, The Music of Life: Biology beyond the Genome
Oxford University Press | ISBN 0199295735 | 2006 | PDF | 1 MB | 177 pages
What is Life? Decades of research have resulted in the full mapping of the human genome - three billion pairs of code whose functions are only now being understood. The gene's eye view of life, advocated by evolutionary biology, sees living bodies as mere vehicles for the replication of the genetic codes. But for a physiologist, working with the living organism, the view is a very different one. Denis Noble is a world renowned physiologist, and sets out an alternative view to the question - one that becomes deeply significant in terms of the living, breathing organism. The genome is not life itself.
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Computational Text Analysis: For Functional Genomics and Bioinformatics

Computational Text Analysis: For Functional Genomics and Bioinformatics

Publisher: Oxford University Press, USA; 1 edition
Language: english
ISBN: 0198567405
Paperback: 312 pages
Format: PDF
Data: A

pril 4, 2006

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Guide to Analysis of DNA Microarray Data

Guide to Analysis of DNA Microarray Data
Publisher: John Wiley & Sons | Pages: 168 | 2004 | ISBN: 0471656046 | PDF | 6.9 MB

Written for biologists and medical researchers who don't have any special training in data analysis and statistics, Guide to Analysis of DNA Microarray Data, Second Edition begins where DNA array equipment leaves off: the image produced by the microarray. The text deals with the questions that arise starting at this point, providing an introduction to microarray technology, then moving on to image analysis, data analysis, cluster analysis, and beyond.
With all chapters rewritten, updated, and expanded to include the latest generation of technology and methods, Guide to Analysis of DNA Microarray Data, Second Edition offers practitioners reliable information using concrete examples and a clear, comprehensible style. This Second Edition features entirely new chapters on:

* Image analysis
* Experiment design
* Automated analysis, integrated analysis, and systems biology
* Interpretation of results
Intended for readers seeking practical applications, this text covers a broad spectrum of proven approaches in this rapidly growing technology. Additional features include further reading suggestions for each chapter, as well as a thorough review of available analysis software.
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Tracking Genetically - Engineered Microorganisms (Biotechnology Intelligence Unit 2)

Tracking Genetically - Engineered Microorganisms (Biotechnology Intelligence Unit 2)
Publisher: LANDES BIOSCIENCE PUBLISHERS | 2000-06-15 | ISBN 1587060094 | Pages: 162 | PDF | 1.8 Mb

This book is an unparalleled, very comprehensive survey of methods for monitoring of specific microorganisms in the environment, with great usefulness for those working in either the assessment of risks of released GMMs or with monitoring of released microorganisms in e.g. soil bioremediation or biocontrol. The aim is to provide a background in different techniques for monitoring of specific microorganisms in environmental samples along with examples of applications of these approaches. The examples include work done in laboratory model systems (microcosms) as well as documentation from actual field releases of genetically modified microorganisms. The regulatory aspects of risk assessment of genetically modified microorganisms targeted for release are also included. Therefore, this book is unique in dealing with different aspects of monitoring of GMMs and should be useful for regulatory agencies that require a summary of existing techniques and information as well as scientists that require a review of the "state-of the art" of modern methods for monitoring specific microorganisms in nature.
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Gregor Mendel: And the Roots of Genetics (Oxford Portraits in Science)
Oxford University Press, USA | 0195122267 | Edition - 1999-03-31 | PDF | 112 pages| 7.26 MB | Rapidshare & Megaupload

When Gregor Mendel passed away in 1884, not a single scholar recognized his epochal contributions to biology. The unassuming abbot of the Augustinian monastery in Brno (in today's Czech Republic) was rediscovered at the turn of the century when scientists were stunned to learn that their findings about inheritance had already been made by an unknown monk three decades earlier. A dedicated researcher who spent every spare hour in the study of the natural sciences, Mendel devised a series of brilliantly simple experiments using a plant easily grown on the monastery's grounds--the garden pea. In the course of just a few years he made the famous discoveries that later became the centerpiece of the science of heredity. In an entertaining and thoroughly informed narrative, Edward Edelson traces Mendel's life from his humble origins to his posthumous fame, giving us both a brief introduction to the fascinating science of genetics and an inspired account of what a modest man can accomplish with dedication and ingenuity. Oxford Portraits in Science is an ongoing series of scientific biographies for young adults. Written by top scholars and writers, each biography examines the personality of its subject as well as the thought process leading to his or her discoveries. These illustrated biographies combine accessible technical information with compelling personal stories to portray the scientists whose work has shaped our understanding of the natural world.

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An Introduction to Forensic Genetics

An Introduction to Forensic Genetics
Publisher: Wiley | Pages:162 | 2007-11-02 | ISBN:0470010266 | PDF| 2.2 MB

An Introduction to Forensic Genetics is a comprehensive introduction to this fast moving area from the collection of evidence at the scene of a crime to the presentation of that evidence in a legal context. The last few years have seen significant advances in the subject and the development and application of genetics has revolutionised forensic science.

This book begins with the key concepts needed to fully appreciate the subject and moves on to examine the latest developments in the field, illustrated throughout with references to relevant casework. In addition to the technology involved in generating a DNA profile, the underlying population biology and statistical interpretation are also covered. The evaluation and presentation of DNA evidence in court is discussed as well with guidance on the evaluation process and how court reports and statements should be presented.

* An accessible introduction to Forensic Genetics from the collection of evidence to the presentation of that evidence in a legal context
* Includes case studies to enhance student understanding
* Includes the latest developments in the field focusing on the technology used today and that which is likely to be used in the future
* Accessible treatment of population biology and statistics associated with forensic evidence

This book offers undergraduate students of Forensic Science an accessible approach to the subject that will have direct relevance to their courses. An Introduction to Forensic Genetics is also an invaluable resource for postgraduates and practising forensic scientists looking for a good introduction to the field.

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Translational Control of Gene Expression (Cold Spring Harbor Monograph Series)

Translational Control of Gene Expression (Cold Spring Harbor Monograph Series)
COLD SPRING HARBOR LABORATORY PRESS | 0879695684 | Edition - 2000| PDF |1020 pages| 6.5 MB | rapidshare & Megaupload

Since the 1996 publication of Translational Control, there has been fresh interest in protein synthesis and recognition of the key role of translational control mechanisms in regulating gene expression. This new monograph updates and expands the scope of the earlier book but it also takes a fresh look at the field. In a new format, the first eight chapters provide broad overviews, while each of the additional twenty-eight has a focus on a research topic of more specific interest. The result is a thoroughly up-to-date account of initiation, elongation, and termination of translation, control mechanisms in development in response to extracellular stimuli, and the effects on the translational machinery of virus infection and disease. This book is essential reading for students entering the field and an invaluable resource for investigators of gene expression and its control.
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Translational Control of Gene Expression

Description: Since the 1996 publication of Translational Control, there has been fresh interest in protein synthesis and recognition of the key role of translational control mechanisms in regulating gene expression. This new monograph updates and expands the scope of the earlier book but it also takes a fresh look at the field. In a new format, the first eight chapters provide broad overviews, while each of the additional twenty-eight has a focus on a research topic of more specific interest. The result is a thoroughly up-to-date account of initiation, elongation, and termination of translation, control mechanisms in development in response to extracellular stimuli, and the effects on the translational machinery of virus infection and disease. This book is essential reading for students entering the field and an invaluable resource for investigators of gene expression and its control.

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Molecular Photofitting: Predicting Ancestry and Phenotype Using DNA

Molecular Photofitting: Predicting Ancestry and Phenotype Using DNA
Academic Press | 0120884925 | Edition - 2007-09-21 | PDF | 634 pages | 10 MB | Rapidshare & Megaupload&Aliceinwire
In the field of forensics, there is a critical need for genetic tests that can function in a predictive or inferential sense, before suspects have been identified, and/or for crimes for which DNA evidence exists but eye-witnesses do not. Molecular Photofitting fills this need by describing the process of generating a physical description of an individual from the analysis of his or her DNA. The molecular photofitting process has been used to assist with the identification of remains and to guide criminal investigations toward certain individuals within the sphere of prior suspects.

Molecular Photofitting provides an accessible roadmap for both the forensic scientist hoping to make use of the new tests becoming available, and for the human genetic researcher working to discover the panels of markers that comprise these tests. By implementing population structure as a practical forensics and clinical genomics tool, Molecular Photofitting serves to redefine the way science and history look at ancestry and genetics, and shows how these tools can be used to maximize the efficacy of our criminal justice system.

* Explains how physical descriptions of individuals can be generated using only their DNA
* Contains case studies that show how this new forensic technology is used in practical application
* Includes over 100 diagrams, tables, and photos to illustrate and outline complex concepts
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The Genetics of Male Fertility

bkThe Genetics of Male Fertility
Humana Press | 1588298639 | Edition - 2004 | PDF | 337 pages| 2.08 MB | Rapidshare & Megaupload

Infertility is a common and severe health problem affecting roughly 7% of the male population. It is likely that the majority of those patients have genetic abnormalities that are the cause of their infertility. In The Genetics of Male Infertility, twenty-one researchers and clinicians review the study of the genetics of male infertility, the tools available in the laboratory and clinic, the current state of knowledge, and the future of research and translation into clinical diagnostics and treatments.
This volume gives special attention to the significant technological advances in the treatment of male infertility, including intracytoplasmic injection (ICSI) in conjunction with in vitro fertilization (IVF). In addition, new tools discussed include in vitro methodologies, in silico technologies, and new model organisms.
Providing a review of our current understanding of genetic causes of male infertility, The Genetics of Male Infertility serves as a guide to evidence-based clinical applications, and a preview of future possibilities.
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Green Gene Technology: Research in an Area of Social Conflict (Advances in Biochemical Engineering / Biotechnology Vol. 107)

Advances in Biochemical Engineering/Biotechnology reviews actual trends in modern biotechnology. Its aim is to cover all aspect sof this interdisciplinary technology where knowledge, methods and expertise are required for chemistry, biochemistry, micro-biology, genetics, chemical engineering and computer science. Specia lvolumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification. They give the state-of-the-art of a topic in a comprehensive way thus being a valuable source for the next 35 years. It also discusses new discoveries and applications. Special volumes are edited by well known guest editors who invite reputed authors for there view articles in their volumes.
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Aging of the Genome: The Dual Role of DNA in Life and Death

Description: Aging has long since been ascribed to the gradual accumulation of DNA mutations in the genome of somatic cells. However, it is only recently that the necessary sophisticated technology has been developed to begin testing this theory and its consequences. Vijg critically reviews the concept of genomic instability as a possible universal cause of aging in the context of a new, holistic understanding of genome functioning in complex organisms resulting from recent advances in functional genomics and systems biology. It provides an up-to-date synthesis of current research, as well as a look ahead to the design of strategies to retard or reverse the deleterious effects of aging. This is particularly important in a time when we are urgently trying to unravel the genetic component of aging-related diseases. Moreover, there is a growing public recognition of the imperative of understanding more about the underlying biology of aging, driven by continuing demographic change.

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Regulation of Gene Expression: Molecular Mechanisms

Regulation of Gene Expression: Molecular Mechanisms
Humana Press | 1588292657 | Edition - 2006 | PDF | 333 pages | 2.88 MB | Rapidshare & Megaupload

Regulation of Gene Expression: Molecular Mechanisms presents a comprehensive overview of methods and approaches for characterizing mechanisms of gene regulation. The text is appropriate both as a graduate textbook and a standard laboratory reference and provides the essential groundwork for an advanced understanding of the various mechanisms that may result in altered activity of a specific cell protein.

Each of three sections explores mechanisms of gene regulation and expression, and presents methods and protocols for achieving specific experimental goals. Part I focuses on approaches for studying control of mRNA expression and determining target genes for a given transcription copy. Part II outlines the methods for determining how proteins can regulate each other by mediating synthesis, degradation, protein-protein interactions, and posttranslational modification. Part III explores how gene targeting techniques in mice can provide insight into protein function. This volume provides a clear, concise overview of the protocols and techniques used to examine chemically or disease-mediated alterations in gene expression in mammalian systems.
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The Genetics of Male Fertility

Douglas T., Ed. Carrell, "The Genetics of Male Fertility"
Humana Press; 1 edition (2004) | ISBN: 1588298639 | 337 pages | PDF | 2,1 Mb

Infertility is a common and severe health problem affecting roughly 7% of the male population. It is likely that the majority of those patients have genetic abnormalities that are the cause of their infertility. In The Genetics of Male Infertility, twenty-one researchers and clinicians review the study of the genetics of male infertility, the tools available in the laboratory and clinic, the current state of knowledge, and the future of research and translation into clinical diagnostics and treatments.

This volume gives special attention to the significant technological advances in the treatment of male infertility, including intracytoplasmic injection (ICSI) in conjunction with in vitro fertilization (IVF). In addition, new tools discussed include in vitro methodologies, in silico technologies, and new model organisms.

Providing a review of our current understanding of genetic causes of male infertility, The Genetics of Male Infertility serves as a guide to evidence-based clinical applications, and a preview of future possibilities.
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Gene Mapping, Discovery, And Expression: Methods And Protocols (Methods in Molecular Biology, Vol 338)

Gene Mapping, Discovery, And Expression: Methods And Protocols (Methods in Molecular Biology, Vol 338)
Humana Press | 1588295753 | Edition - 2006 | PDF | 334 pages | 3.71 MB | Rapidshare & Megaupload

A collection of cutting-edge computational tools and experimental techniques to study how genes are regulated, and to reconstruct the regulatory networks through which various cell-types are produced. On the computational side, web-based technologies to localize genes, to access and retrieve data from microarray databases, to conduct comparative genomics, and to discover the potential "codes" in genomic DNA that may control the expression of protein-coding genes. Detailed experimental techniques described include methods for studying chromatin structure and allele-specific gene expression, methods for high-throughput analysis to characterize the transcription factor binding elements, and methods for isolating and identifying proteins that interact with DNA. The protocols follow the successful Methods in Molecular Biologyâ„¢ series format, each offering step-by-step instructions, an introduction outlining the principles behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding pitfalls.
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Genetics: A Conceptual Approach

Benjamin Pierce, "Genetics: A Conceptual Approach"
W. H. Freeman | ISBN: 1572591609 | December 20, 2002 | PDF | 736 pages | 15730 KB

Designed for introductory genetics courses, "Genetics: A Conceptual Approach" focuses on the important concepts and mechanics of genetics without losing students in a sea of detail. Drawing on more than 20 years of teaching experience, the author makes this often complex subject seem clear and accessible by making important connections between topics, providing advice and encouragement at difficult places, and describing the people, places, and experiments of genetics that make the subject interesting and alive.
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Principles of Developmental Genetics

Principles of Developmental Genetics
Academic Press | 0123695481 | Edition - 2007-06-29 | PDF | 1104 pages | 14.2MB

Unlike anything currently available in the market, Dr. Sally A. Moody and a team of world-renowned experts provide a groundbreaking view of developmental genetics that will influence scientific approaches in embryology, comparative biology, as well as the newly emerging fields of stem cell biology and regenerative medicine. Principles of Developmental Genetics highlights the intersection of developmental biology with new revolutionary genomic technologies, and details how these advances have accelerated our understanding of the molecular genetic processes that regulates development. This definitive resource provides researchers with the opportunity to gain important insights into the clinical applicability of emerging new technologies and animal model data. This book is a must-have for all researchers in genetics, developmental biology, regenerative medicine, and stem cell biology.
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Building Genetic Medicine

In Building Genetic Medicine, Shobita Parthasarathy shows how, even in an era of globalization, national context is playing an important role in the development and use of genetic technologies. Focusing on the development and deployment of genetic testing for breast and ovarian cancer (known as BRCA testing) in the United States and Britain, Parthasarathy develops a comparative analysis framework in order to investigate how national "toolkits" shape both regulations and the architectures of technologies and uses this framework to assess the implications of new genetic technologies.

BRCA testing was one of the most highly anticipated and publicized technologies of contemporary medicine. Parthasarathy argues that differences in the American and British approaches to health care and commercialization of research led to the establishment of different BRCA services in the two countries. In Britain, the technology was available through the National Health Service as an integrated program of counseling and laboratory analysis, and was viewed as a potentially cost-effective form of preventive care. In the United States, although BRCA testing was initially offered by a number of providers, one company eventually became the sole provider of a test available to consumers on demand.

Parthasarathy also reports on an unsuccessful attempt by the American provider of BRCA testing to market its services in Britain. British scientists, health-care providers, and patients rejected the American technology, she argues, because it was part of a social, economic, and political system to which they were not accustomed. Parthasarathy draws lessons for the future of genetic medicine from these cross-national differences, and discusses the ways in which comparative case studies can inform policy-making efforts in science and technology.
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Regulatory RNAs

Regulatory RNAs
Cold Spring Harbor Laboratory Press | 0879698187 | Edition - 2007-06-30 | PDF | 550 pages | 20 MB | rapidshare

This Symposium was attended by 469 scientists from over 25 countries, and the program in-cluded 70 oral presentations and 209 poster presentations. Essential funds to run this meeting were obtained from the National Cancer Institute, a branch of the National Institutes of Health. In addition, financial help from the corporate benefactors, sponsors, affiliates, and contributors of our meetings program is essential for these Symposia to remain a success, and we are most grateful for their continued support.
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Yeast Gene Analysis 2nd edition (Methods in Microbiology: Vol 36)

Yeast Gene Analysis 2nd edition (Methods in Microbiology: Vol 36)
Academic Press | 0123694787 | Edition - July 9, 2007 | PDF | 700 pages | 11.7 MB | rapidshare

Focusing on Saccharomyces cerevisiae, the second edition of Yeast Gene Analysis represents a major reworking of the original edition, with many completely new chapters and major revisions to all previous chapters. Originally published shortly after completion of the yeast genome sequence, the new edition covers many of the major genome-wide strategies that have been developed since then such as microarray analysis of transcription, synthetic gene array studies, protein microarrays and chemical genetic approaches. It represents a valuable resource for any research laboratory using budding yeast as their experimental system in which to identify new yeast gene functions. The chapters are written in a readable style with useful background information, technical tips and specific experimental protocols included as appropriate, enabling both the novice and the experienced yeast researcher to adopt new procedures with confidence.

New chapters on:
* strain construction
* genome-wide two-hybrid approaches
* use of microarrays for transcript analysis
* real-time analysis of chromosome behaviour and FRET
* synthetic gene array technology and protein arrays
* chemical genomics and yeast prions
* RNA gene analysis and mitochondrial gene function analysis
* phylogenetic footprinting
* discovering human gene function and predicting yeast gene function
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Handbook of Immune Response Genes

Handbook of Immune Response Genes

In a vast and rapidly growing body of information, the researcher, clinician and student need resources which bring into focus the latest developments in our understanding of the vertebrate immune system. A concise and up-to-date reference, Handbook of Immune Response Genes does just that. Starting with a brief overview of specific components of the immune system, the authors lead readers toward an understanding which suggests further study. Extensive referencing and a detailed table summarizing the list of CD antigens reinforce this goal.

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Analysis of Genes and Genomes

Richard J. Reece, «Analysis of Genes and Genomes»
John Wiley & Sons | ISBN 0470843799 | 2004 Year | PDF | 7,61 Mb | 490 Pages

This beautifully illustrated textbook provides a clear guide to the tools and techniques of genetic engineering, gene cloning and molecular biology. All aspects of genetic engineering in the post-genomic era are covered, beginning with the basics of DNA structure and DNA metabolism. Using an example-driven approach, the fundamentals of creating mutations in DNA, cloning in bacteria, yeast, plants and animals are all clearly presented.

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The Microbial Models of Molecular Biology: From Genes to Genomes

The Microbial Models of Molecular Biology: From Genes to Genomes
Oxford University Press| 0195154363 | Edition - 2003 | PDF | 337pages| 1.94 MB | Rapidshare & Megaupload

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Genetics: From Genes to Genomes

Genetics: From Genes to Genomes
Product Details
»Book Publisher: McGraw-Hill Science/Engineering/Math (04 March, 2003)
»ISBN: 0072462485
»Book author: Leland Hartwell, Leroy Hood, Michael L. Goldberg, Lee M. Silver, Ruth C. Veres, Ann Reynolds
»Amazon Rating: 3.5

Book Description
Genetics: From Genes to Genomes is a cutting-edge, introductory genetics text authored by an unparalleled author team, including Nobel Prize winner, Leland Hartwell. The Second Edition continues to build upon the integration of Mendelian and molecular principles, providing students with the links between early genetics understanding and the new molecular discoveries that have changed the way the field of genetics is viewed.
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Genes VIII

LEWIN BENJAMIN , GENES 8
Prentice-Hall | ISBN 0131239244 | Edition 8 | CHM | 28Mb

For courses in Molecular Biology, Molecular Genetics, and Gene Regulation. Two decades ago Benjamin Lewin's Genes revolutionized the teaching of molecular biology and molecular genetics by introducing a unified approach to bacteria and higher organisms. Genes has remained at the cutting edge of molecular biology, covering gene structure, organization, and expression. Originally the text opened with the genetic code and worked toward genome structure. Genes VIII changed the approach to begin with the sequence of the human and other genomes and starts with complete coverage of recent advances in genomics. The coverage of genomics is then integrated throughout the text. In striving to maintain currency, the new edition has updated coverage on genome organization, DNA replication, gene regulation and many other new topics.

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Molecular Biology of the Gene

The long-awaited edition of James D. Watson's classic text, Molecular Biology of the Gene, has been thoroughly revised and is published to coincide with the 50th anniversary of Watson and Crick's paper on the structure of the DNA double-helix. Twenty-one concise chapters, co-authored by five highly respected molecular biologists, provide current, authoritative coverage of a fast-changing discipline, giving both historical and basic chemical context. Divided into four parts: Genetics and Chemistry, Central Dogma, Regulation, and Methods. For college instructors, students, and anyone interested in molecular biology and genetics.
pages: 830 pages
Publisher: Benjamin Cummings
ISBN: 080534635X
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From Genes to Genomes: Concepts and Applications of DNA Technology

Rapid advances in our understanding of genetics have required that new books contain topics such as the concept and theory of gene cloning, transgenics, genomics, and various other coverage of traditional and contemporary subjects.

Although there is an abundance of textbooks that cover introductory genetics and advanced courses in genetics, there is a noticeable gap at the intermediate (second year) level. In the past gene structure, function and expression were taught at final year /postgraduate level, but the rapid advances in our understanding of genetics has encouraged courses to change considerably. Over recent years these topics have filtered down the curriculum and are currently taught as core topics at second year, with a corresponding change in textbook requirements. Where once second year students were restricted to learning about the concept and theory of gene cloning, now they routinely clone genes for themselves as part of their practical assignments.

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Molecular Genetics of Bacteria, 4th edition

By Jeremy W. Dale, Simon F. Park, By Jeremy W. Dale, Simon F. Park,

Publisher: Wiley Publisher: Wiley
Number Of Pages: 358 Number Of Pages: 358
Publication Date: 2004-03-12 Publication Date: 2004-03-12
Sales Rank: 863776 Sales Rank: 863776
ISBN / ASIN: 047085085X ISBN / ASIN: 047085085X
EAN: 9780470850855 EAN: 9780470850855
Binding: Paperback Binding: Paperback
Manufacturer: Wiley Manufacturer: Wiley
Studio: Wiley Studio: Wiley
Average Rating: 4 Average Rating: 4

Book Description: Book Description:

The Fourth Edition of this highly successful book provides an essential introduction to the molecular genetics of bacteria. Thoroughly revised and updated, Molecular Genetics of Bacteria now includes a much greater coverage of genomics, microarrays and proteomics. An enhanced treatment of the ways in which both classical and modern genetics have contributed to our understanding of how bacteria work is included. The focus of the book remains firmly on bacteria and will be invaluable to those students studying www.0511668.com microbiology, biotechnology, molecular biology, biochemistry, genetics and related biomedical sciences.Expanded treatment of the development of bacterial structures, cellular communication, quorum sensing and two-component regulation. The Fourth Edition of this highly successful book provides an essential introduction to the molecular genetics of bacteria. Thoroughly revised and updated, Molecular Genetics of Bacteria now includes a much greater coverage of genomics, microarrays and proteomics. An enhanced treatment of the ways in which both classical and modern genetics have contributed to our understanding of how bacteria work is included. The focus of the book remains firmly on bacteria and will be invaluable to those students studying www.0511668.com microbiology, biotechnology, molecular biology, biochemistry, genetics and related biomedical sciences.Expanded treatment of the development of bacterial structures, cellular communication, quorum sensing and two-component regulation.
Provides a distillation of key concepts of bacterial genetics to enhance student understanding.Includes examples of the applications of genetics focusing on bacterial pathogenicity. Provides a distillation of key concepts of bacterial genetics to enhance student understanding.Includes examples of the applications of genetics focusing on bacterial pathogenicity.

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Biology 7th edition by Neil Campbell and Jane Reece

Biology 7th edition
December 2004 | 1312 pages | English | ISBN:080537146X | PDF | 130Mb
Book Description
Neil Campbell and Jane Reece's BIOLOGY remains unsurpassed as the most successful majors biology textbook in the world. This text has invited more than 4 million students into the study of this dynamic and essential discipline.The authors have restructured each chapter around a conceptual framework of five or six big ideas. An Overview draws students in and sets the stage for the rest of the chapter, each numbered Concept Head announces the beginning of a new concept, and Concept Check questions at the end of each chapter encourage students to assess their mastery of a given concept. New Inquiry Figures focus students on the experimental process, and new Research Method Figures illustrate important techniques in biology. Each chapter ends with a Scientific Inquiry Question that asks students to apply scientific investigation skills to the content of the chapter.

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The Rise of Experimental Biology: An Illustrated History

The Rise of Experimental Biology: An Illustrated History
Humana Press| 00896038351 | Edition - 2002-04 | PDF | 216 pages| 8.22 MB | Rapidshare &Megaupload

Peter Lutz, PhD, brilliantly traverses the major milestones along the evolutionary path of biomedicine from earliest recorded times to the dawn of the 20th century. With an engaging narrative that will have you turning "just one more page" well into the night, this book revealingly demonstrates just how the modern scientific method has been shaped by the past. Along the way the reader is treated to some delightfully obscure anecdotes and a treasure trove of rich illustrations that chronicle the tortuous history of biomedical developments, ranging from the bizarre and amusing to the downright macabre. The reader will also be introduced to the major ideas shaping contemporary physiology and the social context of its development, and also gain an understanding of how advances in biological science have occasionally been improperly used to satisfy momentary social or political needs.
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The Biology of the Eye (Advances in Organ Biology: Volume 10)

The Biology of the Eye (Advances in Organ Biology: Volume 10)
Elsevier Science | 0444509259 | Edition - 2006-01-12 | PDF | 406 pages | 1.2 MB | rapidshare

This book is the result of a collective effort. Due to an oversight, mention of three of the contributors who played an especially decisive role in bringing the work to fruition was omitted from the book. They should share fully in the intellectual credits accruing from this publication. I would therefore like to acknowledge and thank the following for their outstanding contributions to editing the work:

Dr. Morten Dornonville la Cour (MD, Dr. Med. Sci.) solicited and edited the chapters on retina, RPE, choroid, vitreous, immunology, and sclera. Dr. la Cour is a Lecturer, Eye Department, Copenhagen University Hospital, specializes in vitreoretinal surgery, and frequently lectures in the international scene. A trained mathematician, he has done research in retinal pigment epithelial physiology in the laboratories of Drs. Thomas Zeuthen and Sheldon Miller.

Dr. Friedrich P.J. Diecke and Dr. Elliott M. Kanner also provided invaluable editorial assistance. Dr Diecke, who was formerly Professor and Chairman of the Department of Physiology, UMDNJ-New Jersey Medical School, is a Professor Emeritus at that institution. His research has concentrated on membrane transport mechanisms in lens epithelial cells, corneal endothelial cells and peripheral nerve and on the regulation of vascular smooth muscle contraction. Dr. Elliott M. Kanner was born in Canada in 1970. He graduated from Yale University in 1992 with a BS/MS degree in Molecular Biophysics and Biochemistry. He received his PhD degree from the Rockefeller University in 1999 and his MD degree from Weill/Cornell in 2001. He is currently an Ophthalmology resident at Columbia University.
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The Biology of Temporary Waters

The Biology of Temporary Waters
Oxford University Press, USA | 0198528124 | Edition - 2006-01-07 | PDF | 352 pages | 5.5 MB | rapidshare

Temporary waters are found throughout the world, and include intermittent streams and ponds, episodic rain puddles, seasonal limestone lakes, the water-retaining structures of plants, such as bromeliads and pitcher plants, and a variety of man-made container habitats. They are probably populated by various plant, animal, and microscopic communities ranging from the very simple to the highly complex. Temporary waters therefore represent fascinating and significant arenas in which to study the properties of species, as the latter deal with the rigours of living in highly variable environments. Obligate temporary water species display a remarkable array of adaptations to the periodic loss of their primary medium that largely set them apart from the inhabitants of permanent water bodies. Survival of individuals frequently depends upon exceptional physiological tolerance or effective migrational abilities that are timed to appropriate habitat phases. Quite apart from their inherent biological interest, temporary waters are now in the limelight from a conservation perspective as these habitats come more and more into conflict with human activities. Traditionally, many temporary waters (be they ponds, pools, streams, or wetlands) have been considered to be 'wasted' areas of land, potentially convertible to agriculture once drained. In reality, they are natural features of the global landscape that represent distinct and unique habitats for many species, some that are found nowhere else and others that reach their maximum abundance and/or genetic diversity there. Temporary waters are also very important from a human health perspective since they function as breeding places for the vectors of many disease organisms, including those that spread malaria, schistosomiasis, yellow fever, and dengue. Most of these exact a high toll in terms of global human suffering and reduced regional economies. This book collates and synthesises the highly scattered and diverse global literature on pure and applied aspects of these habitats and their biota. It examines the ecology of temporary waters in both natural and human environments, and seeks to identify common evolutionary themes. It will be of particular interest to aquatic ecologists, invertebrate and vertebrate biologists, environmental biologists, wetland managers and conservationists, those charged with controlling water-associated diseases, entomologists, educators, and natural historians.
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Phillip E. Pack, Biology (2nd Edition) (Cliffs AP)

Phillip E. Pack, Biology (2nd Edition) (Cliffs AP)
ISBN: 0764586823 | Publisher: Cliffs Notes | Publication Date: 2001-02-06 | Number Of Pages: 416 | pdf | 2,4 mb

CliffsAP study guides help you gain an edge on Advanced Placement* exams. Review exercises, realistic practice exams, and effective test-taking strategies are the key to calmer nerves and higher AP* scores.
CliffsAP Biology, 2nd Edition, is for students who are enrolled in AP Biology or who are preparing for the Advanced Placement Examination in Biology. Inside, you’ll find hints for answering the essay and multiple-choice sections, a clear explanation of the exam format, a look at how exams are graded, and more:

A topic-by-topic look at what’s on the exam
A review of all 12 AP laboratory exercises
Must-know AP Biology essay questions.
Typical answers to free-response questions
Loads of illustrations, graphs, and tables
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M. Abercrombie M. Hickman M.L. Johnson M. Thain, «The Penguin Dictionary of Biology»

M. Abercrombie M. Hickman M.L. Johnson M. Thain, «The Penguin Dictionary of Biology»

ISBN: 0140511776 | Publisher: Penguin USA (P) | Publication Date: 1991-02 | Number Of Pages: 528 | 8.69 Mb | djvu
The Penguin Dictionary of Biology defines some 6,000 terms relating to this rich, complex, and constantly expanding subject—from amino acids, bacteria, and the cell cycle to X-ray diffraction, Ychromosomes, and zygotes. Long established as the definitive single-volume source, the dictionary has now been extensively updated for its eleventh edition. With expanded encyclopedic entries to explain the most crucial concepts, it explores the very latest discoveries and developments, containing more than 400 new entries to take account of the latest thinking on genetics, human physiology, disease, and cell biology. All key botanical and zoological concepts as well as the core vocabulary of biochemistry, immunology, evolutionary theory, and ecology are defined in depth, making this the ideal reference for students, teachers, professionals, and amateur biologists.

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Food Consumption and Disease Risk: Consumer-pathogen Interactions

Food Consumption and Disease Risk: Consumer-pathogen Interactions
CRC Press | ISBN: 0849391571 | 2006-12-13 | PDF | 456 pages | 2.97 Mb | RS

Interactions between foodborne pathogenic agents and consumers that affect the risk of consumers catching foodborne diseases are essential knowledge for microbiologists, R&D and QA staff in the food industry. This collection reviews important issues in the relationship between consumers and foodborne bacteria, viruses and parasites. It presents a broad picture of aspects that increase or decrease exposure to foodborne pathogens, such as globalization of the food supply and trends in food processing. The book addresses host factors that influence foodborne disease (age, genetics and underlying illness) and characteristics of pathogenic agents that influence interaction with human hosts.

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Cheese problems solved

Cheese problems solved
Publisher: CRC | Language: English | ISBN:1420043943 | 402 pages | Data: 2007 | PDF | 2.1 Mb
Description: Arranged in practical question and answer format, Cheese Problems Solved provides responses to more than 200 of the most commonly asked questions about cheese and the cheese making process, from problems arising during the preparation of cheesemilk and cheese ripening to queries regarding cheese analysis and the nutritional profile of cheese. Questions in the latter half of the book concentrate on different types of cheeses, such as Cheddar, blue cheeses and Mozzarella. With contributions from specialists in the field and edited by a leading expert, this book is both an essential basic reference source and problem solving manual for professionals and trainees in the cheese industry.

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International Handbook of Foodborne Pathogens (Food Science and Technology)

International Handbook of Foodborne Pathogens (Food Science and Technology)

CRC Press | ISBN: 0824706854 | 2003-03-18 | PDF | 688 pages | 7.88 Mb | RS

This reference describes the management, control, and prevention of microbial foodborne disease. It analyzes transformations in the epidemiology of foodborne disease from increased transnational food exchange to examinations of new and emerging zoonoses. The authors discuss the prevalence and risk of foodborne disease in developing and industrialized countries. The Annals of Microbiology describes this book as "highly exhaustive, with up to date references." Researchers and practicing pathologists will find this wealth of information vital to continued growth in the field.

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Bernard Wood, Human Evolution: A Very Short Introduction

Bernard Wood, Human Evolution: A Very Short Introduction
Oxford University Press | ISBN 0192803603 | 2005 | PDF | 1 MB | 144 pages

This Very Short Introduction traces the history of paleoanthropology from its beginnings in the eighteenth century to the latest fossil finds. Although concentrating on the fossil evidence for human evolution, it also covers the latest genetic evidence about regional variations in the modern human genome that relate to our evolutionary history. Bernard Wood draws on over thirty years of experience to provide an insider's view of the field and some of the personalities in it, and demonstrates that our understanding of human evolution is critically dependent on advances in related sciences such as paleoclimatology, geochronology, systematics, genetics, and developmental biology.
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Gene Genealogies, Variation and Evolution: A Primer in Coalescent Theory

Gene Genealogies, Variation and Evolution: A Primer in Coalescent Theory
Publisher: Oxford University Press, USA | 2005-01-25 | ISBN: 0198529953 | Pages: 290 | PDF | 2 MB

Coalescent theory tells us what gene genealogies are expected to look like if populations have different demographic histories - i.e, population size, structure, etc. The aim of this book is provide an accessible introduction to Coalescent Theory with a view towards data analysis. CoalescentTheory has in the last two decades moved from being an obscure technique that appealed to mathematical population geneticists to a central tool in data analysis of DNA sequences. The completion of the sequencing of the human genome and accompanying determination of SNPs and haplotypes will increaseits importance even further. This textbook, rich in examples and illustrations, is suitable for a graduate course in statistics, population-, molecular-, and medical genetics.

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Somatostatin Analogs in Diagnostics and Therapy

Somatostatin is a peptide isolated originally from the hypothalamus and considered as an inhibitor of growth hormone secretion. However, further studies have shown that the peptide was ubiquitously distributed and exerts a large spectrum of physiological effects, mostly of an inhibitory nature. The very short half-life of the native peptide limits its therapeutic application. To overcome this limitation the long-lasting modified molecules (analogs) of somatostatin were synthesized. The present book provides comprehensive data on the application of somatostatin analogs in diagnostics and treatment of diseases, mostly endocrine disorders and cancers.

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Regenerative Biology and Medicine

Regenerative Biology and Medicine

The purpose of the book is to bring together in one place the different facets of regenerative biology and medicine while providing the reader with an overview of the basic and clinically-oriented research that is being done. Not only does the content cover a plethora tissues and systems, it also includes information about the developmental plasticity of adult stem cells and the regeneration of appendages.

As part of its balanced presentation, Regenerative Biology and Medicine does address the biological/bioethical issues and challanges involved in the new and exciting field of regenerative biology and medicine.

*Tissues covered include skin, hair, teeth, cornea, and central neural types
*Systems presented are digestive, respiratory, urogenital, musculoskeletal, and cardiovascular
*Includes amphibians as powerful research models
*Discusses appendage regeneration in amphibians and mammals
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Cytokines and Chemokines in Infectious Diseases Handbook (Infectious Disease)

Cytokines and Chemokines in Infectious Diseases Handbook (Infectious Disease)
Humana Press| 896039080 | Edition - 2003-03-03 | PDF | 456 pages| 3.77 MB | Rapidshare &Megaupload

A comprehensive review of what is known about the role of cytokines and chemokines in a variety of human infectious diseases, including gram-negative and -positive infections, listeriosis, mycobacterial infections, lyme arthritis, pneumonia, fungal infections, HIV, leishmaniasis, and sepsis. The authors demonstrate the different cytokine and chemokine production profiles in response to a wide variety of pathogens and the importance of host genetic factors in determining the type and magnitude of responses to a given microorganism. They also critically evaluate the use of cytokines and anticytokines in the treatment of infectious diseases and show how knowledge of cytokine pleiotropic effects, redundancy, and the complexity of the cytokine network has led to better design and better outcomes in cytokine-based therapies for specific infections.
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Bioarrays: From Basics to Diagnostics

Bioarrays: From Basics to Diagnostics
Humana Press | 1588294765 | 2007-06-06 | 270 Pages | 7.32 MB| Rapidshare

Bioarrays: From Basics to Diagnostics provides an integrated and comprehensive collection of timely articles on the use of bioarray techniques in the fields of biotechnology and molecular medicine. The entire volume is broken into four sections – Bioarray Technology Platforms, Biomarkers and Clinical Genomics, Biomarker Identification Using Clinical Proteomics and Glycomics, and Emerging Technologies in Diagnostics – that create one well-integrated work. Particular emphasis is placed on DNA, protein, and carbohydrate biochips. The volume also looks extensively at oligonucleotides, cDNA, proteins, antibodies, and carbohydrate arrays.

Bioarrays: From Basics to Diagnostics will serve as an indispensable reference for graduate students, post-docs, and professors as well as an explanatory analysis for executives and scientists in biotechnology and pharmaceutical companies.
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General Principles of Tumor Immunotherapy: Basic and Clinical Applications of Tumor Immunology

General Principles of Tumor Immunotherapy: Basic and Clinical Applications of Tumor Immunology
Publisher: Springer | Language: English | ISBN:1402060866 | 504 pages | Data: 2007 | PDF | 3 Mb

Description: "General Principles of Tumor Immunotherapy: Basic and Clinical Applications of Tumor Immunology" brings together the world’s leading authorities on tumor immunology. This book describes the basic immunology principles that form the foundation of understanding how the immune system recognizes and rejects tumor cells. The role of the innate and adaptive immune responses is discussed and the implications of these responses for the design of clinical strategies to combat cancer are illustrated through both experimental clinical trials and review of current standard of care therapeutic agents. This information will be invaluable to both students of immunology and cancer research and practicing physicians who have patients with cancer. The book provides a comprehensive overview of the field, demonstrates how advances in basic immunology can and are being applied to cancer, and describes the current status of approved immunotherapy regimens.

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Inborn Errors of Development: The Molecular Basis of Clinical Disorders of Morphogenesis

Inborn Errors of Development: The Molecular Basis of Clinical Disorders of Morphogenesis
Publisher: Oxford University Press | English | ISBN: 019514502X | 1120 pages | 2004 | PDF | 144 Mb

Disorders that affect tissue differentiation, organogenesis, and morphogenesis constitute a significant proportion of human hereditary diseases. Until very recently, however, their genetic causes and pathogenesis have been unknown. Now, with the elucidation of the molecular pathways thatgovern developmental processes and with advances in gene identification, the genetic bases of an increasing number of human disorders of development are being discovered and the links between genotype and phenotype established. This extraordinary volume is the first to present in-depth analyses ofthe human syndromes of abnormal morphogenesis for which the responsible genes have been identified. Following a series of introductory chapters on the general principles of developmental biology, developmental genetics, and the development of individual tissues or organ systems, more than onehundred clinical genetic disorders are considered. The clinical chapters are organized into sections by defined developmental pathways or gene families, and each section is preceded by a general overview. For each disorder the authors cover the disease-causing genes, the role of these genes indevelopment as elucidated in model organisms, the human mutations that have been identified, and the developmental pathogenesis of the condition. Clinical descriptions, along with discussions of therapy and counseling, are provided. This book will be an invaluable resource for physicians,dentists, and other health professionals and for basic scientists interested in developmental processes and genetic perturbations that affect them. It is authoritative, clearly written, consistently organized, and attractively illustrated in color.

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The Chaperonins

The first of its kind, this volume presents the latest research findings on the chaperonins, the best studied family of a class of proteins known as molecular chaperones. These findings are changing our view of some fundamental cellular processes involving proteins, especially how proteins fold into their functional conformations.

Key Features
* Origins of the new view of protein folding
* Prokaryotic chaperonins
* Eukaryotic chaperonins
* Evolution of the chaperonins
* Refolding of denatured proteins
* Organelle biosynthesis
* Biomedical aspects

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