Genome: The Autobiography of a Species in 23 Chapters (P.S.)

Genome: The Autobiography of a Species in 23 Chapters (P.S.)
Harper Perennial | 0060894083 | Edition -2006-06-01 | PDF | 368 pages | 1.57 MB | Rapidshare & Megaupload

The genome's been mapped.But what does it mean? Arguably the most significant scientific discovery of the new century, the mapping of the twenty-three pairs of chromosomes that make up the human genome raises almost as many questions as it answers. Questions that will profoundly impact the way we think about disease, about longevity, and about free will. Questions that will affect the rest of your life.
Genome offers extraordinary insight into the ramifications of this incredible breakthrough. By picking one newly discovered gene from each pair of chromosomes and telling its story, Matt Ridley recounts the history of our species and its ancestors from the dawn of life to the brink of future medicine. From Huntington's disease to cancer, from the applications of gene therapy to the horrors of eugenics, Matt Ridley probes the scientific, philosophical, and moral issues arising as a result of the mapping of the genome. It will help you understand what this scientific milestone means for you, for your children, and for humankind.

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The Microbial Models of Molecular Biology: From Genes to Genomes

The Microbial Models of Molecular Biology: From Genes to Genomes
Oxford University Press| 0195154363 | Edition - 2003 | PDF | 337pages| 1.94 MB | Rapidshare & Megaupload

This book explains the role of simple biological model systems in the growth of molecular biology. Essentially the whole history of molecular biology is presented here, tracing the work in bacteriophages in E. coli, the role of other prokaryotic systems, and also the protozoan and algal models - Paramecium and Chlamydomonas, primarily - and the move into eukaryotes with the fungal systems - Neurospora, Aspergillus and yeast. Each model was selected for its appropriateness for asking a given class of questions, and each spawned its own community of investigators. Some individuals made the transition to a new model over time, and remnant communities of investigators continue to pursue questions in all these models, as the cutting edge of molecular biological research flowed onward from model to model, and onward into higher organisms and, ultimately, mouse and man.

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Denis Noble, The Music of Life: Biology beyond the Genome

Denis Noble, The Music of Life: Biology beyond the Genome
Oxford University Press | ISBN 0199295735 | 2006 | PDF | 1 MB | 177 pages
What is Life? Decades of research have resulted in the full mapping of the human genome - three billion pairs of code whose functions are only now being understood. The gene's eye view of life, advocated by evolutionary biology, sees living bodies as mere vehicles for the replication of the genetic codes. But for a physiologist, working with the living organism, the view is a very different one. Denis Noble is a world renowned physiologist, and sets out an alternative view to the question - one that becomes deeply significant in terms of the living, breathing organism. The genome is not life itself.
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Computational Text Analysis: For Functional Genomics and Bioinformatics

Computational Text Analysis: For Functional Genomics and Bioinformatics

Publisher: Oxford University Press, USA; 1 edition
Language: english
ISBN: 0198567405
Paperback: 312 pages
Format: PDF
Data: April 4, 2006
















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Aging of the Genome: The Dual Role of DNA in Life and Death

Aging of the Genome: The Dual Role of DNA in Life and Death
Publisher: Oxford University Press | Language: English | ISBN: 019856922X | 327 pages | Data: 2007 | PDF | 3 Mb

Description: Aging has long since been ascribed to the gradual accumulation of DNA mutations in the genome of somatic cells. However, it is only recently that the necessary sophisticated technology has been developed to begin testing this theory and its consequences. Vijg critically reviews the concept of genomic instability as a possible universal cause of aging in the context of a new, holistic understanding of genome functioning in complex organisms resulting from recent advances in functional genomics and systems biology. It provides an up-to-date synthesis of current research, as well as a look ahead to the design of strategies to retard or reverse the deleterious effects of aging. This is particularly important in a time when we are urgently trying to unravel the genetic component of aging-related diseases. Moreover, there is a growing public recognition of the imperative of understanding more about the underlying biology of aging, driven by continuing demographic change.

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Analysis of Genes and Genomes

Richard J. Reece, «Analysis of Genes and Genomes»
John Wiley & Sons | ISBN 0470843799 | 2004 Year | PDF | 7,61 Mb | 490 Pages

This beautifully illustrated textbook provides a clear guide to the tools and techniques of genetic engineering, gene cloning and molecular biology. All aspects of genetic engineering in the post-genomic era are covered, beginning with the basics of DNA structure and DNA metabolism. Using an example-driven approach, the fundamentals of creating mutations in DNA, cloning in bacteria, yeast, plants and animals are all clearly presented.

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The Microbial Models of Molecular Biology: From Genes to Genomes

The Microbial Models of Molecular Biology: From Genes to Genomes
Oxford University Press| 0195154363 | Edition - 2003 | PDF | 337pages| 1.94 MB | Rapidshare & Megaupload

This book explains the role of simple biological model systems in the growth of molecular biology. Essentially the whole history of molecular biology is presented here, tracing the work in bacteriophages in E. coli, the role of other prokaryotic systems, and also the protozoan and algal models - Paramecium and Chlamydomonas, primarily - and the move into eukaryotes with the fungal systems - Neurospora, Aspergillus and yeast. Each model was selected for its appropriateness for asking a given class of questions, and each spawned its own community of investigators. Some individuals made the transition to a new model over time, and remnant communities of investigators continue to pursue questions in all these models, as the cutting edge of molecular biological research flowed onward from model to model, and onward into higher organisms and, ultimately, mouse and man.

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Genetics: From Genes to Genomes

Genetics: From Genes to Genomes
Product Details
»Book Publisher: McGraw-Hill Science/Engineering/Math (04 March, 2003)
»ISBN: 0072462485
»Book author: Leland Hartwell, Leroy Hood, Michael L. Goldberg, Lee M. Silver, Ruth C. Veres, Ann Reynolds
»Amazon Rating: 3.5

Book Description
Genetics: From Genes to Genomes is a cutting-edge, introductory genetics text authored by an unparalleled author team, including Nobel Prize winner, Leland Hartwell. The Second Edition continues to build upon the integration of Mendelian and molecular principles, providing students with the links between early genetics understanding and the new molecular discoveries that have changed the way the field of genetics is viewed.
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From Genes to Genomes: Concepts and Applications of DNA Technology

From Genes to Genomes: Concepts and Applications of DNA Technology

Jeremy W. Dale, Malcolm von Schantz, «From Genes to Genomes: Concepts and Applications of DNA Technology»
John Wiley & Sons | ISBN 0471497827 | 2002 Year | PDF | 6,71 Mb | 372 Pages

Rapid advances in our understanding of genetics have required that new books contain topics such as the concept and theory of gene cloning, transgenics, genomics, and various other coverage of traditional and contemporary subjects.

Although there is an abundance of textbooks that cover introductory genetics and advanced courses in genetics, there is a noticeable gap at the intermediate (second year) level. In the past gene structure, function and expression were taught at final year /postgraduate level, but the rapid advances in our understanding of genetics has encouraged courses to change considerably. Over recent years these topics have filtered down the curriculum and are currently taught as core topics at second year, with a corresponding change in textbook requirements. Where once second year students were restricted to learning about the concept and theory of gene cloning, now they routinely clone genes for themselves as part of their practical assignments.

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Flow Cytometry with Plant Cells: Analysis of Genes, Chromosomes and Genomes

Jaroslav Dolezel, Johann Greilhuber, Jan Suda, "Flow Cytometry with Plant Cells: Analysis of Genes, Chromosomes and Genomes"
Wiley-VCH; 1 edition (May 8, 2007) | ISBN: 3527314873 | 479 pages | PDF | 4,3 Mb

Targeted at beginners as well as experienced users, this handy reference explains the benefits and uses of flow cytometery in the study of plants and their genomes. Following a brief introduction that highlights general considerations when analyzing plant cells by flow cytometric methods, the book goes on to discuss examples of application in plant genetics, genomic analysis, cell cycle analysis, marine organism analysis and breeding studies.
With its list of general reading and a glossary of terms, this first reference on FCM in plants fills a real gap by providing first-hand practical hints for the growing community of plant geneticists.

The Zebrafish: Genetics, Genomics and Informatics, Volume 77, Second Edition (Methods in Cell Biology)

The Zebrafish: Genetics, Genomics and Informatics, Volume 77, Second Edition (Methods in Cell Biology)
Academic Press | 0125641729 | Edition - 2004-11-10 | PDF | 630 pages | 9.2 MB | Rapidshare & Megaupload

This volume of Methods in Cell Biology, the second of two parts on the subject of zebrafish, provides a comprehensive compendia of laboratory protocols and reviews covering all the new methods developed since 1999. This second volume covers advances in forward and reverse genetic techniques, provides an update on the zebrafish genome and gene/mutant mapping technologies, examines the new systems for efficient transgenesis in the zebrafish, provides an in-depth view of informatics and the emerging field of comparative genomics, and considers the extensive infrastructure now available to the zebrafish community.

* Details state-of-the art zebrafish protocols, delineating critical steps in the procedures as well as potential pitfalls
* Illustrates many techiques in full-color
* Summarizes the Zebrafish Genome Project [/center]

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Dannie Durand, "Comparative Genomics: RECOMB 2007 International Workshop"

Dannie Durand, "Comparative Genomics: RECOMB 2007 International Workshop"
Publisher: Springer-Verlag | ISBN: 3540749594 | 01 October 2007 | Pages: 193 | 2.9 MB | PDF

This book constitutes the refereed proceedings of the 5th RECOMB Comparative Genomics Satellite Workshop, RECOMB-CG 2007, held in San Diego, CA, USA, in September 2007.

The 14 revised full papers presented were carefully reviewed and selected from 18 initial submissions. The papers address a broad variety of aspects and components of the field of comparative genomics, ranging from quantitative discoveries about genome structure to algorithms for comparative inference to theorems on the complexity of computational problems required for genome comparison.

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Foundations of Comparative Genomics

Foundations of Comparative Genomics
Academic Press | ISBN: 0120887940 | Edition - 2007-03-30 | PDF | 280 pages | 2.4 MB | rapidshare

This book provides an overview of computational analysis of genes and genomes, and of some most notable findings that come out of this work. Foundations of Comparative Genomics presents a historical perspective, beginning with early analysis of individual gene sequences, to present day comparison of gene repertoires encoded by completely sequenced genomes. The author discusses the underlying scientific principles of comparative genomics, argues that completion of many genome sequences started a new era in biology, and provides a personal view on several state-of-the-art issues, such as systems biology and whole-genome phylogenetic reconstructions. This book is an essential reference for researchers and students in computational biology, evolutionary biology, and genetics.

* Presents an historic overview of genome biology and its achievements
* Includes topics not covered in other books such as minimal and ancestral genomes
* Discusses the evolutionary resilience of protein-coding genes and frequent functional convergence at the molecular level
* Critically reviews horizontal gene transfer and other contentious issues
* Covers comparative virology as a somewhat overlooked foundation of modern genome science
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Bioinformatics and Functional Genomics

Bioinformatics and Functional Genomics

Bioinformatics and Functional Genomics

Jonathan Pevsner

ISBN: 978-0-471-21004-7

Paperback

792 pages

November 2003

Review

"…provides non-trivial tools and biological motivations to learn Bioinformatics (Journal of Statistical Computation & Simulation, January 2005)
"...ideal both for biologists who want to master the application of Bioinformatics to real-world problems and for computer scientists who need to understand the biological questions that motivate algorithms." (Quarterly Review of Biology, March-May 2005)
"…this appears to be an excellent textbook for graduate students and upper level undergraduate students." (Annals of Biomedical Engineering, July 2004, 32, 7)
"…highly recommended for academic and medical libraries, and for researchers as an introduction and reference…" (E-Streams, Vol. 7, No. 4)
“...an intriguing work targeted toward biologists wanting to solve problems...provides a compendium of many biological insights and breakthroughs and will be a useful resource...highly recommended.” (Choice, Vol. 41, No. 7, March 2004)

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