Human Brain Proteome, Volume 61 (International Review of Neurobiology)

Human Brain Proteome, Volume 61 (International Review of Neurobiology)
Academic Press | 0123668638 | Edition - 2004-10-13 | PDF | 352 pages | 6.2 MB | Rapidshare & Megaupload

Proteomics is a systematic approach for studying the identity and function of all proteins expressed in a cell, tissue or organ. New drug targets for diseases are often identified by comparing the proteome of the disease state to the normal state. As a result, proteomics has become increasingly important in the pharmaceutical and biotechnology industries as well as academics. This book contains five sections encompassing the research aspects of proteomics on the brain including the most recent advances in the technology and informatics. It discusses advances in high-throughput proteomic technologies and their application to studying neurological disorders such as Alzheimers disease, alcoholism, trauma/stroke, Huntington's disease, and Parkinson's disease. With numerous illustrations to explain the concepts, it provides a comprehensive review on the topic.
* Describes the latest databases and techniques for analyzing the data generated by proteomics
* Outlines the latest developments in proteomic methods
* Provides numerous color illustrations highlighting the application of proteomics to the identification of novel drug targets and biomarkers

Download

Rapidshare

Megaupload

Zinc Finger Proteins: From Atomic Contact to Cellular Function

Zinc Finger Proteins: From Atomic Contact to Cellular Function
Landes Bioscience | English | ISBN: 1417574476 | 276 pages | 2005 | PDF | 8 Mb

Zinc Finger Proteins is the first book to systematically assemble knowledge of various zinc finger proteins belonging to several families and to describe features of zinc finger proteins at levels ranging from atomic to cellular and to organismal. Significance of zinc itself is also addressed as are important domains often associated with zinc fingers. This book is an ideal resource for students who want to learn about zinc finger proteins as well as for scientists who work on gene expression, signal transduction, differentiation, development, cancer and neurological diseases.

Download:
MegaUpload (8 MB)
Depositfiles

Mass Spectrometry of Protein Interactions (Wiley - Interscience Series on Mass Spectrometry)

Mass Spectrometry of Protein Interactions (Wiley - Interscience Series on Mass Spectrometry)
Wiley-Interscience | 0471793736 | Edition - 2007-08-10 | PDF | 137 pages | 2.12 MB | Rapidshare & Megaupload&Aliceinwire

The authoritative guide to analyzing protein interactions by mass spectrometry
Mass spectrometry (MS) is playing an increasingly important role in the study of protein interactions. Mass Spectrometry of Protein Interactionspresents timely and definitive discussions of the diverse range of approaches for studying protein interactions by mass spectrometry with an extensive set of references to the primary literature. Each chapter is written by authors or teams of authors who are international authorities in their fields. This leading reference text:
Discusses the direct detection of protein interactions through electrospray ionization (ESI-MS); ion mobility analysis; and matrix-assisted laser desorption/ionization (MALDI-MS) Covers the indirect analysis of protein interactions through hydrogen-deuterium exchange (HX-MS); limited proteolysis; cross-linking; and radial probe (RP-MS)
Guides researchers in the use of mass spectrometry in structural biology, biochemistry, and protein science to map and define the huge number and diversity of protein interactions Reviews the latest discoveries and applications and addresses new and ongoing challenges This is a comprehensive reference for researchers in academia and industry engaged in studies of protein interactions and an excellent text for graduate and postgraduate students.

Download

Rapidshare

Megaupload

Aliceinwire

Yawen, Ed. Bai, "Protein Folding Protocols "

Yawen, Ed. Bai, "Protein Folding Protocols "
Humana Press; 1 edition (2007) | ISBN: 1588296229 | 327 pages | PDF | 3,6 Mb

Protein Folding Protocols presents protocols for studying and characterizing protein folding from the unfolded to the folded state. Covering experiment and theory, bioinformatics approaches, and state-of-the-art simulation protocols for better sampling of the conformational space, this volume describes a broad range of techniques to study, predict, and analyze the protein folding process.
Protein Folding Protocols also provides sample approaches toward the prediction of protein structure starting from the amino acid sequence, in the absence of overall homologous sequences. These approaches have tremendous implications, ranging from drug design, functional assignment, comprehension of the nature of regulation, understanding molecular machines, viral entry into cells, and putting together cellular pathways and their dynamics.
The protocols follow the successful Methods in Molecular Biologyâ„¢ series format, each one offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.

Download
Depositfiles

Protein Biochemistry and Proteomics (The Experimenter Series)

Protein Biochemistry and Proteomics (The Experimenter Series)
Academic Press | ISBN0:12088545X | Edition - 2006-02-21 | PDF | 256 pages | 3.5 MB | rapidshare&Megaupload

Hubert Rehm's Protein Biochemistry and Proteomics is more than a laboratory manual; it is a strategic guide that provides the reader with tips and tricks for more successful lab experiments. Using a conversational yet professional tone, Rehm provides an overview of a variety of methods in protein biochemistry/proteomics. He provides short and precise summaries of routine procedures as well as listings of the advantages and disadvantages of alternative methods. Readers will immediately sense that the author if very familiar with the challenges, and frustration of the daily lab routine. Never before has such an honest, tactical guide been available for those conducting lab experiments within the field of biochemistry.

Download

Rapidshare

or

Megaupload